Correction of genetic disease by making sense from nonsense
- PMID: 10449426
- PMCID: PMC408532
- DOI: 10.1172/JCI8055
Correction of genetic disease by making sense from nonsense
Comment on
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Aminoglycoside antibiotics restore dystrophin function to skeletal muscles of mdx mice.J Clin Invest. 1999 Aug;104(4):375-81. doi: 10.1172/JCI7866. J Clin Invest. 1999. PMID: 10449429 Free PMC article.
References
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- Howard M, Frizzell RA, Bedwell DM. Aminoglycoside antibiotics restore CFTR function by overcoming premature stop mutations. Nat Med. 1996;2:467–469. - PubMed
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- Bedwell DM, et al. Suppression of a CFTR premature stop mutation in a bronchial epithelial cell line. Nat Med. 1997;3:1280–1284. - PubMed
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- Sicinski P, et al. The molecular basis of muscular dystrophy in the mdx mouse: a point mutation. Science. 1989;244:1578–1580. - PubMed
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