Genetic engineering of doxorubicin production in Streptomyces peucetius: a review
- PMID: 10455495
- DOI: 10.1038/sj.jim.2900673
Genetic engineering of doxorubicin production in Streptomyces peucetius: a review
Abstract
The genetics and biochemistry of daunorubicin and doxorubicin production by Streptomyces peucetius is reviewed, with a focus on how such information can be used for the genetic engineering of strains having improved titers of these two antitumor antibiotics.
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