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Review
. 1999 Jul;23(1):647-52.
doi: 10.1038/sj.jim.2900673.

Genetic engineering of doxorubicin production in Streptomyces peucetius: a review

C R Hutchinson  1 , A L Colombo
Affiliations
Review

Genetic engineering of doxorubicin production in Streptomyces peucetius: a review

C R Hutchinson et al. J Ind Microbiol Biotechnol. 1999 Jul.

Abstract

The genetics and biochemistry of daunorubicin and doxorubicin production by Streptomyces peucetius is reviewed, with a focus on how such information can be used for the genetic engineering of strains having improved titers of these two antitumor antibiotics.

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