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Review
. 1999 Aug;2(4):392-7.
doi: 10.1016/s1369-5274(99)80069-1.

Viruses as triggers of autoimmunity: facts and fantasies

J L Whitton  1 , R S Fujinami
Affiliations
Review

Viruses as triggers of autoimmunity: facts and fantasies

J L Whitton et al. Curr Opin Microbiol. 1999 Aug.

Abstract

Autoimmunity has been proposed as the cause of several human chronic inflammatory diseases, and recent animal studies show that viruses can induce autoimmune disease. These studies demonstrate how viruses might misdirect the immune system, and here we discuss critically the evidence that similar phenomena may lead to human disease.

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