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. 1999 Sep;10(7):280-285.
doi: 10.1016/s1043-2760(99)00169-1.

Genetic Analysis in Fine-needle Aspiration of the Thyroid: A New Tool for the Clinic

D Russo  1 , F Arturi, A Pontecorvi, S Filetti
Affiliations

Genetic Analysis in Fine-needle Aspiration of the Thyroid: A New Tool for the Clinic

D Russo et al. Trends Endocrinol Metab. 1999 Sep.

Abstract

This review will examine the application of genetic analysis to cytological specimens obtained by fine-needle aspiration biopsy in the management of thyroid tumours. In particular, it will consider the use of polymerase chain reaction-based techniques in the diagnosis of the micrometastasis of differentiated thyroid carcinoma to cervical lymph nodes, as well as in the detection of oncogenic alterations in solid thyroid nodules.

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