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Review
. 1999 Sep;15(9):371-7.
doi: 10.1016/s0168-9525(99)01776-x.

Pax 6: mastering eye morphogenesis and eye evolution

W J Gehring  1 , K Ikeo
Affiliations
Review

Pax 6: mastering eye morphogenesis and eye evolution

W J Gehring et al. Trends Genet. 1999 Sep.

Abstract

Pax 6 genes from various animal phyla are capable of inducing ectopic eye development, indicating that Pax 6 is a master control gene for eye morphogenesis. It is proposed that the various eye-types found in metazoa are derived from a common prototype, monophyletically, by a mechanism called intercalary evolution.

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