A change in scientific approach: from alternation to randomised allocation in clinical trials in the 1940s
- PMID: 10463905
- PMCID: PMC1116443
- DOI: 10.1136/bmj.319.7209.572
A change in scientific approach: from alternation to randomised allocation in clinical trials in the 1940s
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Comment in
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Why transition from alternation to randomisation in clinical trials was made.BMJ. 1999 Nov 20;319(7221):1372. doi: 10.1136/bmj.319.7221.1372. BMJ. 1999. PMID: 10567161 Free PMC article. No abstract available.
References
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- MRC Patulin Clinical Trials Committee. Clinical trials of patulin in the common cold. Lancet. 1944;ii:373–375.
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- Clark M. Random thoughts. The evolution of modern clinical trials. Medical Research Council News. 1998;79:24–26.
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- MRC Streptomycin in Tuberculosis Trials Committee. Streptomycin treatment of pulmonary tuberculosis. BMJ. 1948;ii:769–783.
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- Landsborough Thomson A. Half a century of medical research. London: HMSO; 1975. pp. 238–239.
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- Armitage P. Bradford Hill and the randomised controlled trial. Pharm Med. 1992;6:23–37.
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