In-vivo demonstration of dopaminergic degeneration in dementia with Lewy bodies
- PMID: 10466669
- DOI: 10.1016/s0140-6736(99)01178-2
In-vivo demonstration of dopaminergic degeneration in dementia with Lewy bodies
Abstract
With the dopaminergic presynaptic ligand FP-CIT and single photon emission tomography we have shown a severe dopaminergic degeneration in a patient with a necropsy confirmed diagnosis of dementia with Lewy bodies (DLB). We suggest that functional imaging of the nigrostriatal dopamine pathway helps to distinguish DLB from Alzheimer's disease during life.
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