Peptide ligation and its application to protein engineering
- PMID: 10467135
- DOI: 10.1016/s1074-5521(99)80109-4
Peptide ligation and its application to protein engineering
Abstract
The ability to assemble a target protein from a series of peptide fragments, either synthetic or biosynthetic in origin, enables the covalent structure of a protein to be modified in an unprecedented fashion. The present technologies available for performing such peptide ligations are discussed, with an emphasis on how these methodologies have been utilized in protein engineering to investigate biological processes.
Publication types
MeSH terms
Substances
Grants and funding
LinkOut - more resources
Full Text Sources
Other Literature Sources