Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1999 Aug;88(2):181-6.
doi: 10.1016/s1079-2104(99)70115-0.

Actinic cheilitis: a review of 152 cases

G E Kaugars  1 , T Pillion, J A Svirsky, D G Page, J C Burns, L M Abbey
Affiliations

Actinic cheilitis: a review of 152 cases

G E Kaugars et al. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1999 Aug.

Abstract

Objective: The purpose of this study was to determine whether any clinical or histopathologic variables are associated with the severity of epithelial change in lesions of actinic cheilitis.

Study design: A total of 152 acceptable cases of actinic cheilitis were identified from 66,067 cases accessioned from February 1989 to June 1998. For each case, the clinical information supplied by the submitting practitioner at the time of the biopsy and 8 histopathologic variables were evaluated.

Results: The following 5 histopathologic variables were positively correlated with an increased degree of epithelial change: acanthosis, basophilic change within the connective tissue, the presence of inflammation within the connective tissue, perivascular inflammation, and thickness of the keratin layer. None of the clinical variables was associated with an increased degree of epithelial change.

Conclusions: The presence of any of the aforementioned histopathologic changes should prompt a close evaluation of the lesion for the presence of either epithelial dysplasia or carcinoma.

PubMed Disclaimer

LinkOut - more resources