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Clinical Trial
. 1999 Aug 28;354(9180):739.
doi: 10.1016/S0140-6736(99)03557-6.

Acute effect of nitric oxide on Raynaud's phenomenon in scleroderma

R R Freedman, R Girgis, M D Mayes
Clinical Trial

Acute effect of nitric oxide on Raynaud's phenomenon in scleroderma

R R Freedman et al. Lancet. .

Abstract

Intra-arterial infusions of L-arginine and sodium nitroprusside significantly decreased the occurrence of laboratory-induced Raynaud's phenomenon in scleroderma patients. Raising the concentration of nitric oxide may be of therapeutic value in this population.

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