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. 1999 Jul;31(7):471-5.
doi: 10.1023/a:1003760026681.

Thrombospondin is sequentially expressed and then de-expressed during early pregnancy in the rat uterus

M Slater  1 , C R Murphy
Affiliations

Thrombospondin is sequentially expressed and then de-expressed during early pregnancy in the rat uterus

M Slater et al. Histochem J. 1999 Jul.

Abstract

The expression of thrombospondin on Day 1, Day 3 and Day 6 of pregnancy has been examined in the rat, using light microscopic immunoperoxidase and electron immunogold techniques. The glycoprotein was expressed in the apical, lateral and basal uterine epithelium on Days 1 and 3 but was then de-expressed at the time of implantation on Day 6. We propose that these data suggest a role for thrombospondin in remodellig the uterine epithelium during the plasma membrane transformation, but that it does not play a part in attachment and implantation.

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