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Comparative Study
. 1999 Aug;87(2):306-8.
doi: 10.1046/j.1365-2672.1999.00899.x.

Human immune responses to the UK human anthrax vaccine

L W Baillie  1 , K Fowler, P C Turnbull
Affiliations
Comparative Study

Human immune responses to the UK human anthrax vaccine

L W Baillie et al. J Appl Microbiol. 1999 Aug.

Abstract

The IgG anti-protective antigen subclass antibody response of individuals who had been infected with anthrax was compared with that of healthy individuals immunized with the UK licensed anthrax vaccine. The predominant subclass in both groups was IgG1. In addition, IgG3 was seen in convalescent serum while vaccinees produced IgG2, IgG3 and IgG4 subclass. The significance of these results is discussed. Further work is required to determine the role of antibodies in mediating protective immunity in man.

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