Mutational status of Ig V(H) genes provides clinically valuable information in B-cell chronic lymphocytic leukemia

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M Naylor et al. Blood. 1999.

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. 1999 Sep 15;94(6):1837-9.

¹ Oklahoma Medical Research Foundation, Oklahoma City, OK; and the University of Oklahoma Health Sciences Center, Oklahoma City, OK.

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Ig V gene mutation status and CD38 expression as novel prognostic indicators in chronic lymphocytic leukemia.
Damle RN, Wasil T, Fais F, Ghiotto F, Valetto A, Allen SL, Buchbinder A, Budman D, Dittmar K, Kolitz J, Lichtman SM, Schulman P, Vinciguerra VP, Rai KR, Ferrarini M, Chiorazzi N. Damle RN, et al. Blood. 1999 Sep 15;94(6):1840-7. Blood. 1999. PMID: 10477712
Unmutated Ig V(H) genes are associated with a more aggressive form of chronic lymphocytic leukemia.
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