Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1999 Sep;100(3):148-55.
doi: 10.1111/j.1600-0404.1999.tb00730.x.

A health-related quality of life questionnaire for multiple sclerosis patients

L E Pfennings  1 , H M Van der Ploeg, L Cohen, I Bramsen, C H Polman, G J Lankhorst, L Vleugels
Affiliations

A health-related quality of life questionnaire for multiple sclerosis patients

L E Pfennings et al. Acta Neurol Scand. 1999 Sep.

Abstract

Objective: The construction of a brief, valid and reliable HRQoL questionnaire for use in multiple sclerosis patients based on generic and disease-specific HRQoL measures.

Material and methods: The Medical Outcomes Study 36-item Short Form Health Survey (SF-36), COOP/ WONCA Charts, and Disability & Impact Profile (DIP) were used in a longitudinal study in 162 patients with multiple sclerosis.

Results: Factor analyses identified 2 underlying dimensions of HRQoL, relating to "physical functioning" and "psychological functioning". Selection of the 3 highest loading reliable scales on each factor resulted in a final questionnaire consisting of 3 scales of the SF-36 and 3 scales of the DIP. In total 40 items were selected; completion time is about 10 min.

Conclusion: The final questionnaire adequately measured 2 dimensions of HRQoL. The length of the questionnaire is acceptable for patients with MS in view of respondent burden.

PubMed Disclaimer

Publication types

LinkOut - more resources