Intravenous immunoglobulin therapy: confounding effects on serological screening for toxoplasmosis during pregnancy
- PMID: 10488226
- PMCID: PMC85593
- DOI: 10.1128/JCM.37.10.3423-3424.1999
Intravenous immunoglobulin therapy: confounding effects on serological screening for toxoplasmosis during pregnancy
Abstract
The serological diagnosis of toxoplasmic infection during pregnancy is intended to prevent congenital infection of the fetus. However, in the context of recurrent pregnancy loss intravenous immunoglobulin therapy can create a biological trap for the interpretation of serological results, with potentially serious consequences for the outcome of the pregnancy.
References
-
- Fortier B, Ajana F, Valat A S, Bouchez M C. Interférence des immunoglobulines polyvalentes dans la sérologie toxoplasmique. Ann Biol Clin. 1992;50:265–266. - PubMed
-
- Hohlfeld P H, Daffos F, Costa J M, Thulliez P, Forestier F, Vidaud M. Prenatal diagnosis of congenital toxoplasmosis with a polymerase-chain-reaction test on amniotic fluid. N Engl J Med. 1994;331:695–699. - PubMed
-
- Kiprov D D, Nachtigall R D, Weaver R C, Jacobson A, Main E K, Garovoy M R. The use of intravenous immunoglobulin in recurrent pregnancy loss associated with combined alloimmune and autoimmune abnormalities. Am J Reprod Immunol. 1996;36:228–234. - PubMed
-
- Lichtiger B, Rogge K. Spurious serologic test results in patients receiving infusions of intravenous immune gammaglobulin. Arch Pathol Lab Med. 1991;115:467–469. - PubMed
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical
