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Review
. 1998:33:43-52.
doi: 10.1042/bse0330043.

Mitochondria in the life and death of neurons

S L Budd  1 , D G Nicholls
Affiliations
Review

Mitochondria in the life and death of neurons

S L Budd et al. Essays Biochem. 1998.

Abstract

A prolonged decrease in ATP levels underlies a number of neurodegenerative disorders. Defects in oxidative phosphorylation are associated with a number of neurodegenerative disorders. Mitochondria also play an important role in mediating the initiation of apoptosis.

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