Case Reports
doi: 10.1212/wnl.53.4.871.
Globus pallidus deep brain stimulation for generalized dystonia: clinical and PET investigation
Affiliations
- PMID: 10489059
- DOI: 10.1212/wnl.53.4.871
Item in Clipboard
Case Reports
Globus pallidus deep brain stimulation for generalized dystonia: clinical and PET investigation
Neurology.
.
Abstract
Bilateral globus pallidus internus (GPi) deep brain stimulation (DBS) in a patient with severe idiopathic generalized dystonia resulted in immediate improvement of all aspects of dystonia. During joystick movement, GPi DBS reduced PET activation bilaterally in the primary motor, lateral premotor, supplementary motor, anterior cingulate, and prefrontal areas and ipsilaterally in the lentiform nucleus. Altering basal ganglia function with GPi DBS reverses the overactivity of certain motor cortical areas present in dystonia.
Similar articles
-
Globus pallidus internus stimulation in primary generalized dystonia: a H215O PET study.Brain. 2004 Aug;127(Pt 8):1899-908. doi: 10.1093/brain/awh213. Epub 2004 Jul 1. Brain. 2004. PMID: 15231585
-
Comparison of Short-Term Stimulation of the Globus Pallidus Interna and Subthalamic Nucleus for Treatment of Primary Dystonia.World Neurosurg. 2019 Mar;123:e211-e217. doi: 10.1016/j.wneu.2018.11.137. Epub 2018 Nov 24. World Neurosurg. 2019. PMID: 30481618
-
Functional and Structural Connectivity Patterns Associated with Clinical Outcomes in Deep Brain Stimulation of the Globus Pallidus Internus for Generalized Dystonia.AJNR Am J Neuroradiol. 2020 Mar;41(3):508-514. doi: 10.3174/ajnr.A6429. Epub 2020 Feb 13. AJNR Am J Neuroradiol. 2020. PMID: 32054614 Free PMC article.
-
The physiological effects of pallidal deep brain stimulation in dystonia.IEEE Trans Neural Syst Rehabil Eng. 2007 Jun;15(2):166-72. doi: 10.1109/TNSRE.2007.896994. IEEE Trans Neural Syst Rehabil Eng. 2007. PMID: 17601185 Review.
-
Placement of deep brain stimulators into the subthalamic nucleus or Globus pallidus internus: technical approach.Stereotact Funct Neurosurg. 2002;79(3-4):118-45. doi: 10.1159/000070828. Stereotact Funct Neurosurg. 2002. PMID: 12890973 Review.
Cited by
-
Neuromodulation in Dystonia - Harnessing the Network.Adv Neurobiol. 2023;31:177-194. doi: 10.1007/978-3-031-26220-3_10. Adv Neurobiol. 2023. PMID: 37338702
-
Pallidotomy for Dystonia: A Neglected Procedure?Mov Disord. 2021 Mar;36(3):533-534. doi: 10.1002/mds.28409. Mov Disord. 2021. PMID: 33749921 Free PMC article. No abstract available.
-
Abnormal structure-function relationships in hereditary dystonia.Neuroscience. 2009 Nov 24;164(1):220-9. doi: 10.1016/j.neuroscience.2008.12.041. Epub 2009 Jan 1. Neuroscience. 2009. PMID: 19162138 Free PMC article. Review.
-
Reconfigurable MRI technology for low-SAR imaging of deep brain stimulation at 3T: Application in bilateral leads, fully-implanted systems, and surgically modified lead trajectories.Neuroimage. 2019 Oct 1;199:18-29. doi: 10.1016/j.neuroimage.2019.05.015. Epub 2019 May 13. Neuroimage. 2019. PMID: 31096058 Free PMC article.
-
Outcome of pallidal deep brain stimulation for treating isolated orofacial dystonia.Acta Neurochir (Wien). 2022 Sep;164(9):2287-2298. doi: 10.1007/s00701-022-05320-9. Epub 2022 Jul 27. Acta Neurochir (Wien). 2022. PMID: 35896828
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical
