Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1999 May;6(3):445.
doi: 10.1128/CDLI.6.3.445-445.1999.

Diagnosis of Lyme borreliosis by a whole-blood gamma interferon assay for cell-mediated immune responses

Diagnosis of Lyme borreliosis by a whole-blood gamma interferon assay for cell-mediated immune responses

V K Sikand et al. Clin Diagn Lab Immunol. 1999 May.
No abstract available

PubMed Disclaimer

Figures

FIG. 1
FIG. 1
IFN-γ production in whole blood from Lyme patients and control subjects stimulated with a B. burgdorferi cell sonicate. The cutoff (mean of control samples + 3 standard deviations) is indicated by a dashed line.

References

    1. Dattwyler R J, Volkman D J, Luft B J, Halperin J J, Thomas J, Golightly G M. Dissociation of specific T- and B-lymphocyte responses to Borrelia burgdorferi. 1988;319:1441–1446. - PubMed
    1. Desem N, Jones S L. Development of a human gamma interferon enzyme immunoassay and comparison with tuberculin skin testing for detection of Mycobacterium tuberculosis infection. Clin Diagn Lab Immunol. 1998;5:531–536. - PMC - PubMed
    1. Forsberg P, Ernerudh J, Ekerfelt C, Roberg M, Vrethem M, Bergstrom S. The outer surface proteins of Lyme disease Borrelia spirochetes stimulate T cells to secrete interferon-gamma (IFN-γ); diagnostic and pathogenic implications. Clin Exp Immunol. 1995;101:453–460. - PMC - PubMed
    1. Pohl-Koppe A, Balashov K E, Steere A C, Logigian E L, Hafler D A. Identification of a T cell subset capable of both IFN-γ and IL-10 secretion in patients with chronic Borrelia burgdorferi infection. J Immunol. 1998;160:1804–1810. - PubMed

Substances