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Review
. 1999 Sep;264(2):281-6.
doi: 10.1046/j.1432-1327.1999.00623.x.

Snake venom alpha-neurotoxins and other 'three-finger' proteins

V Tsetlin  1
Affiliations
Free article
Review

Snake venom alpha-neurotoxins and other 'three-finger' proteins

V Tsetlin. Eur J Biochem. 1999 Sep.
Free article

Abstract

The review is mainly devoted to snake venom alpha-neurotoxins which target different muscle-type and neuronal nicotinic acetylcholine receptors. The primary and spatial structures of other snake venom proteins as well as mammalian proteins of the Ly-6 family, which structurally resemble the 'three-finger' snake proteins, are also briefly discussed. The main emphasis is placed on recent data characterizing the alpha-neurotoxin interactions with nicotinic acetylcholine receptors.

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