Review
doi: 10.1097/00041552-199907000-00007.
Novel findings about 24,25-dihydroxyvitamin D: an active metabolite?
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- PMID: 10491738
- DOI: 10.1097/00041552-199907000-00007
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Review
Novel findings about 24,25-dihydroxyvitamin D: an active metabolite?
Curr Opin Nephrol Hypertens.
1999 Jul.
Abstract
The physiological role of 24,25-dihydroxyvitamin D remains controversial. Recent results suggest that 24,25-dihydroxyvitamin D is essential for fracture healing, and binding sites for 24,25-dihydroxyvitamin D have been identified in fracture callus tissue. Mice deficient in the 25-hydroxyvitamin D-24-hydroxylase enzyme provide novel genetic tools in which to study the role of 24,25-dihydroxyvitamin D in bone development and fracture repair.
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