Expression of an unidentified immunoglobulin isotype on rabbit Ig-bearing lymphocytes
- PMID: 105045
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Expression of an unidentified immunoglobulin isotype on rabbit Ig-bearing lymphocytes
J Immunol.
1979 Feb.
Abstract
A non-IgM immunoglobulin molecule was found on most rabbit Ig-bearing lymphocytes isolated from mesenteric lymph nodes. Membrane bound immunoglobulin light chains and heavy chains were detected by immunofluorescence and by rosetting with antibody-coated erythrocytes on mesenteric lymph node cells stripped of IgM by anti-IgM allotype antibodies. The percentage of cells bearing these residual immunoglobulin molecules was similar to the percentage of cells bearing immunoglobulin before "stripping" with anti-IgM antibody. These residual immunoglobulin molecules were not IgA nor IgG and are believed to be the rabbit analogue of human IgD.
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