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Comment
. 1999 Oct;6(10):903-5.
doi: 10.1038/13264.

Deconstructing heme

S I Beale, J I Yeh
Comment

Deconstructing heme

S I Beale et al. Nat Struct Biol. 1999 Oct.

Abstract

Heme degradation plays important biological roles, ranging from generating light-absorbing compounds in plants to facilitating iron homeostasis in mammals. The X-ray crystal structure of human heme oxygenase-1, which instigates the degradation process, reveals insights into the enzymatic mechanism of this important process.

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