Review
doi: 10.1016/s1369-5274(99)00012-0.
Evolution of the linear DNA replicons of the Borrelia spirochetes
Affiliations
- PMID: 10508719
- DOI: 10.1016/s1369-5274(99)00012-0
Item in Clipboard
Review
Evolution of the linear DNA replicons of the Borrelia spirochetes
Curr Opin Microbiol.
1999 Oct.
Abstract
Members of the spirochete genus Borrelia carry numerous linear DNA replicons with covalently closed hairpin telomeres. The genome of one member of this genus, B. burgdorferi B31, has now been completely characterized and contains a linear chromosome, twelve linear plasmids and nine circular extra-chromosomal elements. The phylogenetic position of the Borrelia spirochetes strongly suggests that a progenitor with circular replicons acquired the ability to replicate linear DNA molecules.
Similar articles
-
Telomere exchange between linear replicons of Borrelia burgdorferi.J Bacteriol. 2004 Jul;186(13):4134-41. doi: 10.1128/JB.186.13.4134-4141.2004. J Bacteriol. 2004. PMID: 15205414 Free PMC article.
-
Linear plasmids of Borrelia burgdorferi have a telomeric structure and sequence similar to those of a eukaryotic virus.J Bacteriol. 1991 Nov;173(22):7233-9. doi: 10.1128/jb.173.22.7233-7239.1991. J Bacteriol. 1991. PMID: 1938918 Free PMC article.
-
Telomere resolution in the Lyme disease spirochete.EMBO J. 2001 Jun 15;20(12):3229-37. doi: 10.1093/emboj/20.12.3229. EMBO J. 2001. PMID: 11406599 Free PMC article.
-
Structure, function, and evolution of linear replicons in Borrelia.Annu Rev Microbiol. 2010;64:185-202. doi: 10.1146/annurev.micro.112408.134037. Annu Rev Microbiol. 2010. PMID: 20536352 Review.
-
Hairpin telomeres and genome plasticity in Borrelia: all mixed up in the end.Mol Microbiol. 2005 Nov;58(3):625-35. doi: 10.1111/j.1365-2958.2005.04872.x. Mol Microbiol. 2005. PMID: 16238614 Review.
Cited by
-
Telomere exchange between linear replicons of Borrelia burgdorferi.J Bacteriol. 2004 Jul;186(13):4134-41. doi: 10.1128/JB.186.13.4134-4141.2004. J Bacteriol. 2004. PMID: 15205414 Free PMC article.
-
Characterization of the telomerase modulating activities of yeast DNA helicases.Methods Enzymol. 2021;661:327-342. doi: 10.1016/bs.mie.2021.08.005. Epub 2021 Sep 6. Methods Enzymol. 2021. PMID: 34776218 Free PMC article.
-
High-throughput plasmid content analysis of Borrelia burgdorferi B31 by using Luminex multiplex technology.Appl Environ Microbiol. 2011 Feb;77(4):1483-92. doi: 10.1128/AEM.01877-10. Epub 2010 Dec 17. Appl Environ Microbiol. 2011. PMID: 21169439 Free PMC article.
-
Function and evolution of plasmid-borne genes for pyrimidine biosynthesis in Borrelia spp.J Bacteriol. 2006 Feb;188(3):909-18. doi: 10.1128/JB.188.3.909-918.2006. J Bacteriol. 2006. PMID: 16428394 Free PMC article.
-
Bidirectional replication from an internal ori site of the linear N15 plasmid prophage.Nucleic Acids Res. 2003 Nov 15;31(22):6552-60. doi: 10.1093/nar/gkg856. Nucleic Acids Res. 2003. PMID: 14602914 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
