Sense and specificity: a molecular identity for nociceptors
- PMID: 10508737
- DOI: 10.1016/S0959-4388(99)00009-4
Sense and specificity: a molecular identity for nociceptors
Abstract
Recent cloning efforts have identified families of ligand- or voltage-gated ion channels that are expressed by pain-sensing primary afferent neurons. Pharmacological, electrophysiological and genetic studies are beginning to reveal how these signaling molecules specify roles for subsets of sensory neurons in the pain pathway.
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