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Review
. 1999 Oct;9(5):525-30.
doi: 10.1016/S0959-4388(99)00009-4.

Sense and specificity: a molecular identity for nociceptors

M J Caterina  1 , D Julius
Affiliations
Review

Sense and specificity: a molecular identity for nociceptors

M J Caterina et al. Curr Opin Neurobiol. 1999 Oct.

Abstract

Recent cloning efforts have identified families of ligand- or voltage-gated ion channels that are expressed by pain-sensing primary afferent neurons. Pharmacological, electrophysiological and genetic studies are beginning to reveal how these signaling molecules specify roles for subsets of sensory neurons in the pain pathway.

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