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Review
. 1999 Oct;9(5):517-24.
doi: 10.1016/S0959-4388(99)00015-X.

Lineages and transcription factors in the specification of vertebrate primary sensory neurons

D J Anderson  1
Affiliations
Review

Lineages and transcription factors in the specification of vertebrate primary sensory neurons

D J Anderson. Curr Opin Neurobiol. 1999 Oct.

Abstract

Recent advances have indentified some of the key transcriptional regulators of mammalian genes, the neurogenins. Neurogenins 1 and 2 appear to control distinct sublineages for different classes of sensory neurons, including a 'pioneer' lineage for proprioceptors specified early in neural crest migration. Neurogenins act via a cascade of downstream transcriptional regulators, some of which have been identified.

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