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. 1999 Oct;94(4):595-9.
doi: 10.1016/s0029-7844(99)00308-7.

Thrombotic risk during pregnancy: a population study

P Lindqvist  1 , B Dahlbäck, K Marŝál
Affiliations

Thrombotic risk during pregnancy: a population study

P Lindqvist et al. Obstet Gynecol. 1999 Oct.

Abstract

Objective: To determine the incidence of pregnancy-related venous thromboembolic events and the relationship to selected risk factors such as maternal age, parity, smoking, preeclampsia, or cesarean delivery.

Methods: All Swedish women reported as having pregnancy-related venous thromboembolic events during 1990-1993 (608 of 479,422 deliveries) were compared with all thrombosis-free Swedish pregnant women during 1993 (114,940).

Results: The incidence of pregnancy-related venous thromboembolic events was 13 per 10,000 deliveries. Cesarean delivery was associated with a fivefold increased risk of venous thromboembolic events. Advanced age was not a significant risk factor itself, but was associated with an age-related increase in frequency of cesareans. Women with preeclampsia were at a threefold higher risk postpartum, but at no increased risk before delivery. There was a tobacco consumption-dependent increase in the risk of thrombosis among smokers.

Conclusion: The incidence of pregnancy-related thrombosis was 13 per 10,000 and provided new insights to important risk factors such as age, cesarean delivery, smoking, and preeclampsia.

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