[The use of pharmacological tests for the diagnosis of the nature of bronchial obstruction in coal miners with premorbid stage of chronic dust-related bronchitis]

Abstract

Bronchospasm in premorbid chronic dust bronchitis in coal miners is caused mostly by dystonic effects of sympathetic and parasympathetic nervous system, and minimally by hypersecretion and swelling of respiratory tract mucosa. Pathogenetic features of obstruction in premorbid chronic dust bronchitis are lower sympathetic tone (major feature) and higher parasympathetic tone (minor one). Those items should be considered in therapeutic and prophylactic tactics.