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. 1999 Sep;62(9):1319-21.
doi: 10.1021/np990134u.

Antibacterial diterpenoid acids from Azorella compacta

G A Wächter  1 , G Matooq, J J Hoffmann, W M Maiese, M P Singh, G Montenegro, B N Timmermann
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Antibacterial diterpenoid acids from Azorella compacta

G A Wächter et al. J Nat Prod. 1999 Sep.

Abstract

The two novel diterpenoid acids mulin-12,14-dien-11-on-20-oic acid (1) and mulin-12-ene-11,14-dion-20-oic acid (2) have been isolated from Azorella compacta. Their structures have been elucidated by 1D and 2D NMR methods. In contrast to the closely related known mulinolic acid (3) and its dehydration product (4) these new natural products have been shown to exhibit antimicrobial activity.

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