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Clinical Trial
. 1999 Sep;47(3):206-9.

Botulinum toxin treatment of hemifacial spasm and blepharospasm: objective response evaluation

A Thussu  1 , C R Barman, S Prabhakar
Affiliations
  • PMID: 10514580
Free article
Clinical Trial

Botulinum toxin treatment of hemifacial spasm and blepharospasm: objective response evaluation

A Thussu et al. Neurol India. 1999 Sep.
Free article

Abstract

Twenty seven patients with hemifacial spasm (HFS) and sixteen patients with blepharospasm (BS) having mean Jankovic disability rating scale score of 2.56+0.58 SD and 2.81+0.54 SD, respectively, were treated with botulinum toxin A (BTX-A) injections. The total number of injection sessions were ninety one with relief response in 98.91%. The mean improvement in function scale score was 3.78+0.64 SD and 3.29+1.07 SD respectively, in HFS and BS groups. The clinical benefit induced by botulinum toxin lasted for a mean of 4.46+3.11 SD (range 2 to 13) months in HFS group and 2.66+1.37 SD (range 1 to 6) months, in BS groups. Transient ptosis was seen in 4.39% of total ninety one injection sessions. These findings show that local botulinum toxin treatment provides effective, safe and long lasting relief of spasms.

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