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Review
. 1999 Aug-Oct;25(8-10):427-33.
doi: 10.1007/BF02944294.

Basic therapy for rheumatoid arthritis: nonsteroidal anti-inflammatory drugs

K F Daoud  1 , C G Jackson, H J Williams
Affiliations
Review

Basic therapy for rheumatoid arthritis: nonsteroidal anti-inflammatory drugs

K F Daoud et al. Compr Ther. 1999 Aug-Oct.

Abstract

Nonsteroidal anti-inflammatory drugs (NSAIDs) are often the initial treatment for rheumatoid arthritis. NSAID-induced inhibition of cyclooxygenase-2 (COX2) and cyclooxygenase-1 appears to correlate with clinical efficacy and toxicity, respectively. Newer NSAIDs with greater COX2 selectivity offer the promise of less toxic therapy.

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