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. 1999 Jul-Aug;46(28):2451-3.

Treatment of spontaneous ruptured hepatocellular carcinoma

H Yoshida  1 , M Onda, T Tajiri, M Umehara, Y Mamada, S Matsumoto, K Yamamoto, M Kaneko, T Kumazaki
Affiliations
  • PMID: 10522018

Treatment of spontaneous ruptured hepatocellular carcinoma

H Yoshida et al. Hepatogastroenterology. 1999 Jul-Aug.

Abstract

Background/aims: Spontaneous rupture with bleeding is a potentially life-threatening complication of hepatocellular carcinoma (HCC). We review our experience with treatments of ruptured HCC.

Methodology: Between January 1988 and December 1997, 18 patients with ruptured HCC were admitted. The patients were divided into 4 groups according to the treatment type of ruptured HCC. Group 1 consisted of 10 patients treated by transarterial embolization (TAE) followed by elective hepatectomy. Group 2 consisted of 2 patients treated by only TAE. Group 3 consisted of 3 patients treated by emergency operation. Group 4 consisted of 3 patients who could not be treated by TAE or surgery.

Results: In Group 1, 4 of the 10 patients died; 3 from recurrent HCC and 1 from cerebral hemorrhage, and hospital mortality was absent. The 1-year survival rate was 87.5%. In Group 2, both patients recovered sufficiently well to be discharged. The 1-year survival rate was 50%. In Groups 3 and 4, hospital mortality rate was 100%.

Conclusions: TAE followed by elective hepatectomy was an effective treatment in patients with ruptured HCC.

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