Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 1999 Oct;104(8):1001-6.
doi: 10.1172/JCI8124.

Airway remodeling in asthma

J A Elias  1 , Z Zhu, G Chupp, R J Homer
Affiliations
Review

Airway remodeling in asthma

J A Elias et al. J Clin Invest. 1999 Oct.
No abstract available

PubMed Disclaimer

Figures

Figure 1
Figure 1
Autopsy specimen illustrating inflammation and remodeling responses in the asthmatic airway. (a) Airway inflammation and a central mucus plug (asterisk). ×10. (b) Increased muscle mass (asterisk) and submucosal gland hypertrophy (arrow). ×25. (c) Subepithelial fibrosis (asterisk) and eosinophilic infiltration (arrow). ×100.
See this image and copyright information in PMC

References

    1. Lange P, Parner J, Vestbo J, Schnohr P, Jensen G. A 15-year follow-up study of ventilatory function in adults with asthma. N Engl J Med. 1998;339:1194–1200. - PubMed
    1. Peat JK, Woolcock AJ, Cullen K. Rate of decline of lung function in subjects with asthma. Eur J Respir Dis. 1987;70:171–179. - PubMed
    1. Holgate ST, Wilson JR, Howarth PH. New insights into airway inflammation by endobronchial biopsy. Am Rev Respir Dis. 1992;145:S2–S6. - PubMed
    1. Bradding, P., Redington, A.E., and Holgate, S.T. 1997. Airway wall remodelling in the pathogenesis of asthma: cytokine expression in the airways. In Airway wall remodelling in asthma. A.G. Stewart, editor. CRC Press. Boca Raton, FL. 29–63.
    1. Robinson DS, et al. Predominant Th2-like bronchoalveolar T-lymphocyte population in atopic asthma. N Engl J Med. 1992;326:298–304. - PubMed

Publication types