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. 1975 Nov;2(11):2007-20.
doi: 10.1093/nar/2.11.2007.

Construction of a double-stranded deoxyribonucleotide sequence of 45 base pairs designed to code for S-peptide 2-14 of bovine ribonuclease A

C L Harvey, K Olson, A de Czekala, A L Nussbaum
Free PMC article

Construction of a double-stranded deoxyribonucleotide sequence of 45 base pairs designed to code for S-peptide 2-14 of bovine ribonuclease A

C L Harvey et al. Nucleic Acids Res. 1975 Nov.
Free PMC article

Abstract

An artificial DNA duplex, each strand consisting of 45 monomers, is constructed from chemically synthesized deoxyriboöligonucleotides. The resulting bihelical polymer may code for a modified S-peptide of Ribonuclease A. This is the first synthetic duplex designed to code for a eukaryotic message.

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