Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1999 Oct 1;144(2):145-51.
doi: 10.1016/s0304-3835(99)00223-2.

High incidence of synchronous cancer of the oral cavity and the upper gastrointestinal tract

K Fukuzawa  1 , Y Noguchi, T Yoshikawa, A Saito, C Doi, T Makino, Y Takanashi, T Ito, A Tsuburaya
Affiliations

High incidence of synchronous cancer of the oral cavity and the upper gastrointestinal tract

K Fukuzawa et al. Cancer Lett. .

Abstract

A high incidence of synchronous esophageal or gastric carcinoma in preoperative patients with carcinoma of the oral cavity was reported. Esophageal carcinoma was found in seven out of 56 patients (12.5%) and gastric cancer in five patients (8.9%) by videoendoscopy aided with lugol staining in the esophagus and indigocarmine solution in the stomach, although all patients were completely asymptomatic for these lesions. All patients were male, regular drinkers and heavy smokers. The depth of invasion of such tumors was limited to either mucosa or submucosa. Those esophageal and gastric lesions beside the primary oral cancers were positive for p53 protein by immunohistochemistry. Careful preoperative evaluation of not only the esophagus but also the stomach should be a routine procedure in patients with carcinoma of the oral cavity.

PubMed Disclaimer

LinkOut - more resources