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Review
. 1999 Oct 21;9(20):R776-8.
doi: 10.1016/S0960-9822(00)80011-1.

Cancer biology: extracellular proteinases in malignancy

L M Matrisian  1
Affiliations
Free article
Review

Cancer biology: extracellular proteinases in malignancy

L M Matrisian. Curr Biol. .
Free article

Abstract

Secreted, matrix-degrading proteinases have been viewed as contributing to tumor metastasis. A recent study indicates that the gene for one of these enzymes, the matrix metalloproteinase stromelysin-1, can actually cause cancer when expressed in transgenic mice.

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