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Clinical Trial
. 1999 Oct 15;84(8):934-7, A7.
doi: 10.1016/s0002-9149(99)00471-3.

Effects of fluvastatin on prothrombotic and fibrinolytic factors in type 2 diabetes mellitus

K C Tan  1 , E D Janus, K S Lam
Affiliations
Clinical Trial

Effects of fluvastatin on prothrombotic and fibrinolytic factors in type 2 diabetes mellitus

K C Tan et al. Am J Cardiol. .

Abstract

The effects of fluvastatin therapy on parameters of coagulation and fibrinolysis were evaluated in patients with diabetic dyslipidemia in a randomized, placebo-controlled study. Fluvastatin therapy was associated with a small reduction in factor VII coagulant activity, von Willebrand factor, and in plasminogen activator inhibitor 1 and tissue plasminogen activator antigens, but the effects of fluvastatin on hemostatic factors were much less marked than its effects on plasma lipids.

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