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Comment
. 1999 Oct 26;96(22):12219-21.
doi: 10.1073/pnas.96.22.12219.

Making sense of polymer-based biosensors

P S Heeger, A J Heeger
Comment

Making sense of polymer-based biosensors

P S Heeger et al. Proc Natl Acad Sci U S A. .
No abstract available

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Figures

Figure 1
Figure 1
Chemical structure of a single repeat unit of the luminescent polymer MPS-PPV.
Figure 2
Figure 2
Schematic representation of a polymer biosensor. (A) Quencher-Biotin is removed by avidin and results in fluorescence as performed by Chen et al. (1). (B) Quencher linked to an antibody may be removed from the polymer by its specific antigen and result in fluorescence. (C) Quencher linked to an oligonucleotide may be removed from the polymer by a specific complementary sequence of DNA or RNA and result in fluorescence.
See this image and copyright information in PMC

Comment on

References

    1. Chen L, McBranch D W, Wang H-L, Helgeson R, Wudl F, Whitten D G. Proc Nat Acad Sci USA. 1999;96:12287–12292. - PMC - PubMed
    1. Bredas J L, Silbey R, editors. Conjugated Polymers. Dordrecht, The Netherlands: Kluwer; 1991.
    1. Salaneck W R, Lundström I, Rånby B, editors. Conjugated Polymers and Related Materials: The Interconnection of Chemical and Electronic Structure. Oxford: Oxford Univ. Press; 1993.
    1. Heeger A, Kivelson S, Schrieffer J, Su W. Rev Mod Phys. 1988;60:781–850. - PubMed
    1. Heeger A. Solid State Commun. 1998;107:673–679.

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