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Review
. 1999 Nov;24(11):428-32.
doi: 10.1016/s0968-0004(99)01462-0.

How membrane proteins travel across the mitochondrial intermembrane space

C M Koehler  1 , S Merchant, G Schatz
Affiliations
Review

How membrane proteins travel across the mitochondrial intermembrane space

C M Koehler et al. Trends Biochem Sci. 1999 Nov.

Abstract

A newly discovered family of small proteins in the yeast mitochondrial intermembrane space mediates import of hydrophobic proteins from the cytoplasm into the inner membrane. Loss of one of these chaperone-like proteins from human mitochondria results in a disease that causes deafness, muscle weakness and blindness.

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