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. 1999 Nov;43(11):2790-2.
doi: 10.1128/AAC.43.11.2790.

In vitro susceptibilities of Neisseria gonorrhoeae to fatty acids and monoglycerides

G Bergsson  1 , O Steingrímsson, H Thormar
Affiliations

In vitro susceptibilities of Neisseria gonorrhoeae to fatty acids and monoglycerides

G Bergsson et al. Antimicrob Agents Chemother. 1999 Nov.

Abstract

The susceptibility of Neisseria gonorrhoeae to several medium-chain fatty acids and their 1-monoglycerides was tested at a short inactivation time of 1 min. The results indicate that monocaprin, a monoglyceride of capric acid (10 carbon atoms, no double bonds), causes the fastest and most effective killing of all strains of N. gonorrhoeae tested.

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Figures

FIG. 1
FIG. 1
Inactivation of N. gonorrhoeae by incubation with 2.5 mM solutions of fatty acids and monoglycerides for 1 min at room temperature. The bars represent reduction of CFU. In the bars, the asterisks indicate that the reduction of titer was equal to or greater than 6.0 log10 CFU. Caprylic acid and monocaprylin (8:0) (number of carbon atoms/number of double bonds), capric acid and monocaprin (10:0), lauric acid and monolaurin (12:0), myristic acid and monomyristin (14:0), palmitoleic acid and monopalmitolein (16:1), and oleic acid and monoolein (18:1) are shown.
See this image and copyright information in PMC

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