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. 1975 Jan;72(1):358-61.
doi: 10.1073/pnas.72.1.358.

A general model for genetic recombination

M S Meselson, C M Radding

A general model for genetic recombination

M S Meselson et al. Proc Natl Acad Sci U S A. 1975 Jan.

Abstract

A general model is proposed for genetic recombination. Its essential new feature is the hypothesis that recombination is initiated by a single-strand (or asymmetric) transfer, which may, after isomerization, become a two-strand (or symmetric) exchange. The likelihood of this transition from asymmetric to symmetric strand exchange determines certain characteristic features of recombination in any particular organism.

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References

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