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Review
. 1999 Nov;6(6):365-70.
doi: 10.1097/00062752-199911000-00002.

Search for an unrelated HLA-compatible stem cell donor

E Roosnek  1 , J M Tiercy
Affiliations
Review

Search for an unrelated HLA-compatible stem cell donor

E Roosnek et al. Curr Opin Hematol. 1999 Nov.

Abstract

Through recent advancements in tissue-typing techniques, the true extent of HLA polymorphism has become evident. This has allowed a better assessment of the degree of matching of donor and recipient, which has reiterated the pivotal importance of HLA compatibility for the outcome of a stem cell transplantation. Now that most tissue typing laboratories are technically able to provide a flawless, high-resolution HLA typing, the challenge of the future will be to develop tissue typing-based search strategies that give an optimal chance to find the best donor within the time limits set by the disease of the patient.

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