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. 1999 Nov;135(5):644-6.
doi: 10.1016/s0022-3476(99)70065-x.

Cerebral vasoreactivity to arterial carbon dioxide tension in preterm infants: the effect of ibuprofen

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Cerebral vasoreactivity to arterial carbon dioxide tension in preterm infants: the effect of ibuprofen

F Mosca et al. J Pediatr. 1999 Nov.

Abstract

Cerebral vasoreactivity to CO(2), calculated by linear regression of total cerebral hemoglobin, measured by near infrared spectroscopy, and corresponding PaCO(2), in infants <32 weeks' gestation, was found to be unaffected by the administration of ibuprofen, which was given on the first postnatal day as prophylaxis against patent ductus arteriosus.

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