doi: 10.1073/pnas.72.2.447.
Murine leukemia virus: detection of unintegrated double-stranded DNA forms of the provirus
- PMID: 1054828
- PMCID: PMC432328
- DOI: 10.1073/pnas.72.2.447
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Murine leukemia virus: detection of unintegrated double-stranded DNA forms of the provirus
Proc Natl Acad Sci U S A.
1975 Feb.
Abstract
Infection of JLS V-9 (mouse bone marrow) cells with Moloney murine leukemia virus leads to appearance of virus-specific DNA in the low molecular weight DNA fraction from infected cells. Most of this DNA is double-stranded. Two discrete forms of double-stranded DNA, both of molecular weight 6 times 10-6, have been characterized. One of these forms is closed-circular, supercoiled DNA; the other form is a mixture of nicked-circular and linear DNA.
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