doi: 10.1016/s0021-9673(99)00841-9.
Analysis of taxol and major taxoids in Himalayan yew, Taxus wallichiana
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- PMID: 10551356
- DOI: 10.1016/s0021-9673(99)00841-9
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Analysis of taxol and major taxoids in Himalayan yew, Taxus wallichiana
J Chromatogr A.
.
Abstract
A reversed-phase column liquid chromatography method for the analysis of taxol, 10-deacetylbaccatin III, baccatin IV, 1-hydroxybaccatin I, 2-acetoxybrevifoliol, brevifoliol, 2'-deacetoxydecinnamoyltaxinine J and 2'-deacetoxytaxinine J in yew needles has been developed using a Nova-Pak Phenyl column and a binary gradient profile. The various aspects of analysis such as extraction efficiency, detection limits, reproducibility and peak purity were validated using UV-Vis as well as photodiode array detection.
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