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. 1999 Oct 30;354(9189):1524-5.
doi: 10.1016/S0140-6736(99)04265-8.

Immunoassay for urothelial cancers that detects DNA replication protein Mcm5 in urine

K Stoeber, I Halsall, A Freeman, R Swinn, A Doble, L Morris, N Coleman, N Bullock, R A Laskey, C N Hales, G H Williams

Immunoassay for urothelial cancers that detects DNA replication protein Mcm5 in urine

K Stoeber et al. Lancet. .

Abstract

Cancer-screening tests for internal organs are severely constrained by low specificity or sensitivity, cost, and morbidity. We report a non-invasive immunofluorometric assay for detection of urothelial cancers based on ectopic expression of the DNA replication protein Mcm5.

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