Definitive evidence that the murine C-type virus inducing locus Akv-1 is viral genetic material
- PMID: 1055389
- PMCID: PMC432430
- DOI: 10.1073/pnas.72.3.906
Definitive evidence that the murine C-type virus inducing locus Akv-1 is viral genetic material
Abstract
DNA of the AKR mouse contains a set of murine leukemia virus sequences that are not present in DNA of the NIH Swiss mouse. NIH mice partially congenic for the AKR murine-leukemia-virus-inducing locus Akv-1 contain this set of sequences, and, in a three-point cross segregating for Akv-1 on an NIH background, the sequences segregated with Akv-1. It is concluded that the Akv-1 locus contains viral sequences.
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