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Clinical Trial
. 1999 Oct 15:94 Suppl 3:58-61.
doi: 10.1007/BF03042194.

[Molecular biology studies of a multicenter phase III study (SIC Study)]

[Article in German]
T Zimmermann  1 , S Albrecht, G von Gagern
Affiliations
Clinical Trial

[Molecular biology studies of a multicenter phase III study (SIC Study)]

[Article in German]
T Zimmermann et al. Med Klin (Munich). .

Abstract

Transcription factors adjust the up- and downregulation of inflammatory genes. Within the bounds of the SIC-study (Selenium in Intensive Care) the authors will investigate the role of transcription factors NF-kappa B and AP-1 in S.I.R.S/septic patients. The goal of these investigations is the corroboration of therapy of septic patients with sodium selenite at the molecular biological level.

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