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. 1999 Nov 13;319(7220):1302.
doi: 10.1136/bmj.319.7220.1302.

Brain imaging: the NMR revolution. Interview by Clare Thompson

J W Prichard, J R Alger, R Turner

Brain imaging: the NMR revolution. Interview by Clare Thompson

J W Prichard et al. BMJ. .
No abstract available

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Figures

Figure 1
Figure 1
Magnetic resonance images 9.5 hours after onset of clinical stroke syndrome. Diffusion weighted imaging (DWI) shows hyperintense signal from physiologically damaged tissue surrounding right sylvian fissure—conventional T2 weighted imaging shows only subtle changes in same region. Magnetic resonance angiography (MRA) shows flow void in right internal carotid and middle cerebral arteries
Figure 2
Figure 2
Functional magnetic resonance image of normal subject performing finger movements (conventional coronal magnetic resonance image in grey). Coloured regions identify tissue in which blood flow increases to meet extra metabolic requirements of task
Figure 3
Figure 3
(Top) Spectroscopic image of patient with glioblastoma multiforme. Colour images display topographical distribution of intensities of NMR signals from several cerebral metabolites including total choline, total creatine, N-acetylaspartate, lactate, and lipid. (Bottom) Tissue section examined displayed by conventional magnetic resonance imaging. Metabolite signals can be displayed as spectra from volumes (white squares) referenced to magnetic resonance image (graphs). Compared with right frontal lobe, neoplastic tissue in left frontal lobe shows increased choline, lactate, and lipid signals but decreased N-acetylaspartate signals
See this image and copyright information in PMC

References

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    1. Warach S, Gaa J, Siewert B, Wielopolski P, Edelman RR. Acute human stroke studied by whole brain echo planar diffusion-weighted magnetic resonance imaging. Ann Neurol. 1995;37:231–241. - PubMed

Publication types